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GIT
1_Ranitidine mechanism is :
a.reversible block H1_receptors
b. reversible block M1_receptors
c.competitive block H2_receptors
d. Block proton pump
2_cimitidine is :
a- H1_receptors antagonist
B- has No D-D-I
C- may cause impotence & gynecomastia
D_ all of above
3- PPIs , which is wrong :
A- prodrugs
B- given on empty stomach
C_ given trice daily
D- dose reduction is necessary in severe liver damage
4_adverse effects of PPIs :
A- vit B12_ absorption increases
B- hypogastrinemia
C- osteoporosis
D- drug interactions with esomeprazole
5_ esomeprazole is better than omeprazole because :
A- stronger
B- not toxic
C- not affect drugs like clopidogrel
D- very longer
6-pirenzepine :
A- Analgesic
B- major drug in peptic ulcer
C- limited use due to high adverse effects
D- it raises PH of stomach
7-which drug is PG analoge , & contraindicated in pregnancy :
A- omeprazole
B- cimitidine
C- misorostol
D-metoclopramide
8- antacids :
A- sodium bicarbonate localy act
B- magnesium hydroxide may produce consipation
C- aluminium hydroxide may produce constipation
D- thay decrease. HCL secretion
9- sucralfate mechanism :
A- coat the ulcer for 24 hours
B- form viscous coat for 48 hours
C- it needs acidic media for activation
D_ it prevents Hcl secretion
10- sucralfate :
A- given antacids
B-given on full stomach
C- given on empty stomach
D_ it may produce diarrhea
11- metoclopramide mechansim :
A- block D2_ receptors in heart
B- block D1_ receptors
C- block D2_receptors. In CTZ.
D- block M1* receptors.
12_ domperidone is better than metoclopramide in :
A- stronger antiemetic
B- stronger prokinetic
C- No extrapyramidal symptoms
D- stronger antacids
13_which drugs used in motion sickness :
A- hyoscine ,metoclopramide
B- meclizine , domperidone
C- cyclizine , scoploamine
D- ondansetron , cortisone
Ψ14_tardive dyskinesia is side effects of :
A- cimitidine
B- domperidone
C- metoclopramide
D- chloramphenicol
15_ which is best antiemetic. For. Vomiting during cancer chemotherapy :
A- 5HT3_receptor agonist
B- H1_receptor agonist
C- 5HT3_ receptor antagonist
D- D2_receptor antagonist
BY Pharmacology with Dr.Ayman aldaqwali 2nd Yr dentistry ππ¦·β¨
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