✅پاسخ سوال ۶۱
❗️یکی از مکانیسم های تولرانس محیطی سلول T که سبب آنرژی می شود وجود یوبی کوئیتین لیگاز CBL-b است که در صورت شناسایی آنتی ژن خودی در غیاب کمک محرک سبب یوبیکوئیتینه شدن TCR و تخریب آن توسط پروتئازوم می شود
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BY کانال چکیده ایمونولوژی
Telegram is a cloud-based instant messaging service that has been making rounds as a popular option for those who wish to keep their messages secure. Telegram boasts a collection of different features, but it’s best known for its ability to secure messages and media by encrypting them during transit; this prevents third-parties from snooping on messages easily. Let’s take a look at what Telegram can do and why you might want to use it.
The super secure UAE-based Telegram messenger service, developed by Russian-born software icon Pavel Durov, is looking to raise $1bn through a bond placement to a limited number of investors from Russia, Europe, Asia and the Middle East, the Kommersant daily reported citing unnamed sources on February 18, 2021.The issue reportedly comprises exchange bonds that could be converted into equity in the messaging service that is currently 100% owned by Durov and his brother Nikolai.Kommersant reports that the price of the conversion would be at a 10% discount to a potential IPO should it happen within five years.The minimum bond placement is said to be set at $50mn, but could be lowered to $10mn. Five-year bonds could carry an annual coupon of 7-8%.
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