🟡Second therapy phase (20-40 minutes of seizure activity)
🌸خط دوم که معمولا در اورژانس انجام میشود؛ فنی توئین، فوس فنی توئین، سدیم والپورات، لووتیراستام
when response (or lack of response) to the initial therapy should be apparent. Reasonable options include fosphenytoin, valproic acid and levetiracetam.
- Intravenous fosphenytoin (20mg/PE, Max 1500mg/PE -- Single dose) Or;
-Intravenousvalproic acid (40mg/kg, Max 3000mg/dose -- Single dose) Or;
- Intravenouslevetiracetam (60mg/kg, Max 4500mg/dose, -- Single dose)
🌸 در صورت عدم دسترسی به ۳ داروی بالا، میتوان از فنوباربیتال وریدی سینگل دوز 15mg/kg استفاده کرد. 🌸 There is no clear evidence that any one of these options is better than the others. Because of adverse events, IV phenobarbital is a reasonable second-therapy alternative if none of the three recommended therapies are available.
🟡Second therapy phase (20-40 minutes of seizure activity)
🌸خط دوم که معمولا در اورژانس انجام میشود؛ فنی توئین، فوس فنی توئین، سدیم والپورات، لووتیراستام
when response (or lack of response) to the initial therapy should be apparent. Reasonable options include fosphenytoin, valproic acid and levetiracetam.
- Intravenous fosphenytoin (20mg/PE, Max 1500mg/PE -- Single dose) Or;
-Intravenousvalproic acid (40mg/kg, Max 3000mg/dose -- Single dose) Or;
- Intravenouslevetiracetam (60mg/kg, Max 4500mg/dose, -- Single dose)
🌸 در صورت عدم دسترسی به ۳ داروی بالا، میتوان از فنوباربیتال وریدی سینگل دوز 15mg/kg استفاده کرد. 🌸 There is no clear evidence that any one of these options is better than the others. Because of adverse events, IV phenobarbital is a reasonable second-therapy alternative if none of the three recommended therapies are available.
Telegram auto-delete message, expiring invites, and more
elegram is updating its messaging app with options for auto-deleting messages, expiring invite links, and new unlimited groups, the company shared in a blog post. Much like Signal, Telegram received a burst of new users in the confusion over WhatsApp’s privacy policy and now the company is adopting features that were already part of its competitors’ apps, features which offer more security and privacy. Auto-deleting messages were already possible in Telegram’s encrypted Secret Chats, but this new update for iOS and Android adds the option to make messages disappear in any kind of chat. Auto-delete can be enabled inside of chats, and set to delete either 24 hours or seven days after messages are sent. Auto-delete won’t remove every message though; if a message was sent before the feature was turned on, it’ll stick around. Telegram’s competitors have had similar features: WhatsApp introduced a feature in 2020 and Signal has had disappearing messages since at least 2016.
The lead from Wall Street offers little clarity as the major averages opened lower on Friday and then bounced back and forth across the unchanged line, finally finishing mixed and little changed.The Dow added 33.18 points or 0.10 percent to finish at 34,798.00, while the NASDAQ eased 4.54 points or 0.03 percent to close at 15,047.70 and the S&P 500 rose 6.50 points or 0.15 percent to end at 4,455.48. For the week, the Dow rose 0.6 percent, the NASDAQ added 0.1 percent and the S&P gained 0.5 percent.The lackluster performance on Wall Street came on uncertainty about the outlook for the markets following recent volatility.
