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世界首例基因编辑猪肝移植人体成功 为器官短缺提供突破性方案

中科院院士窦科峰团队利用经6处基因编辑的猪肝脏,移植至一名脑死亡但体征稳定的患者体内,同时保留其自身肝脏以模拟肝衰竭支持治疗。移植后10天观察期内,猪肝在人体内正常分泌胆汁、血供稳定,未出现超急性排斥反应及猪内源性逆转录病毒传播。该成果获《自然》杂志认定为异种器官移植领域里程碑。

研究严格遵循学术及伦理审查程序,移植对象为家属同意参与的脑死亡患者,实验在伦理委员会监督下完成,10天后因家属意愿终止。此前,基因编辑猪心脏、肾脏移植人体的案例已逐步推进,但肝脏移植因血液供应复杂性更具挑战。

牛津大学教授彼得·弗兰德称该技术“非常精妙”,为临床应用奠定基础。通过基因编辑技术减少免疫排斥风险,异种移植或成解决全球器官短缺的关键路径。

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世界首例基因编辑猪肝移植人体成功 为器官短缺提供突破性方案

中科院院士窦科峰团队利用经6处基因编辑的猪肝脏,移植至一名脑死亡但体征稳定的患者体内,同时保留其自身肝脏以模拟肝衰竭支持治疗。移植后10天观察期内,猪肝在人体内正常分泌胆汁、血供稳定,未出现超急性排斥反应及猪内源性逆转录病毒传播。该成果获《自然》杂志认定为异种器官移植领域里程碑。

研究严格遵循学术及伦理审查程序,移植对象为家属同意参与的脑死亡患者,实验在伦理委员会监督下完成,10天后因家属意愿终止。此前,基因编辑猪心脏、肾脏移植人体的案例已逐步推进,但肝脏移植因血液供应复杂性更具挑战。

牛津大学教授彼得·弗兰德称该技术“非常精妙”,为临床应用奠定基础。通过基因编辑技术减少免疫排斥风险,异种移植或成解决全球器官短缺的关键路径。

新华社
Nature

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How Does Bitcoin Work?

Bitcoin is built on a distributed digital record called a blockchain. As the name implies, blockchain is a linked body of data, made up of units called blocks that contain information about each and every transaction, including date and time, total value, buyer and seller, and a unique identifying code for each exchange. Entries are strung together in chronological order, creating a digital chain of blocks. “Once a block is added to the blockchain, it becomes accessible to anyone who wishes to view it, acting as a public ledger of cryptocurrency transactions,” says Stacey Harris, consultant for Pelicoin, a network of cryptocurrency ATMs. Blockchain is decentralized, which means it’s not controlled by any one organization. “It’s like a Google Doc that anyone can work on,” says Buchi Okoro, CEO and co-founder of African cryptocurrency exchange Quidax. “Nobody owns it, but anyone who has a link can contribute to it. And as different people update it, your copy also gets updated.”

Look for Channels Online

You guessed it – the internet is your friend. A good place to start looking for Telegram channels is Reddit. This is one of the biggest sites on the internet, with millions of communities, including those from Telegram.Then, you can search one of the many dedicated websites for Telegram channel searching. One of them is telegram-group.com. This website has many categories and a really simple user interface. Another great site is telegram channels.me. It has even more channels than the previous one, and an even better user experience.These are just some of the many available websites. You can look them up online if you’re not satisfied with these two. All of these sites list only public channels. If you want to join a private channel, you’ll have to ask one of its members to invite you.

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