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基因编辑创世纪：Colossal复活灭绝万年的恐狼

生物技术公司Colossal宣布通过CRISPR技术成功复活已灭绝1万年的恐狼，三只幼崽Romulus、Remus和Khaleesi分别于2024年10月及2025年1月诞生。该技术基于俄亥俄州1.3万年前的牙齿化石和爱达荷州7.2万年前的耳骨化石提取的完整基因组，对灰狼进行14个关键基因编辑，标志着灭绝物种复活技术首次实现商业化应用。恐狼作为更新世时期北美的顶级掠食者，其复活为研究古生态系统提供了活体样本，同时引发关于生物伦理与生态平衡的全球讨论。

公司同步推进猛犸象复活计划，已完成25个基因改造，目标2028年诞生首只胚胎。

公司强调此举旨在推动地球生态修复，践行"人类有责任使地球恢复健康状态"的核心使命。此次突破使Colossal估值达102亿美元，其技术已衍生出塑料降解与AI药物开发子公司。生态学家警告，复活物种可能破坏现有生态平衡，需警惕"非预期后果"。

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Create: 2025-04-07
Last Update: 2025-05-06 23:51:50

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